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PMCID: PMC4633518

3 The role of MGBA and neuroinflammation in ASD pathophysiology The MGBA is composed of complex interactions among the gut microbiota, the mucosal immune system, the enteric nervous system, the autonomic nervous system, and the central nervous system, which receives input primarily through the vagus nerve (Ullah et al., 2023)

The shift toward parasympathetic tone reduces resting heart rate variability, decreases cardiac workload, and promotes arterial relaxation

Provide essential fatty acids , including omega-3 fats, that support brain and heart health

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