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Then, articles were scanned and the data from these studies was extracted, including the number of patients per arm, L-carnitine dosing (including initial loading dosing and daily oral maintenance dosing), acute MI (AMI) index event type, follow-up duration, and outcomes (i.e., all-cause mortality, adverse cardiovascular events including unstable angina, acute MI, heart failure, and ventricular arrythmia)

An invited commentary on this study, also published in JAMA Ophthalmology, challenges the idea that the increased risk of NAION among semaglutide users resulted directly from the medication

J Clin Endocrinol Metab 81(1):327332 Zinman B, Hoogwerf BJ, Durn Garca S, Milton DR, Giaconia JM, Kim DD et al (2007) The effect of adding exenatide to a thiazolidinedione in suboptimally controlled type 2 diabetes: a randomized trial

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