RASL1 Polyclonal Antibody, 100ul RNA Synthesis The encoded protein may act

The encoded protein may act as a guanine nucleotide exchange factor

Isoform 1 C-terminal region is tyrosine-rich

and studies in mice suggest that it regulates the activity of defensins in intestinal mucosa

a cytosolic phosphoprotein implicated in tumorigenesis

Other variants may be present

RASL1 Polyclonal Antibody, 100ul RNA Synthesis The encoded protein may actThe protein encoded by this gene is member of the GAP1 family of GTPase activating proteins. These proteins stimulate the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP bound form of RAS, thereby allowing control of cellular proliferation and differentiation. This particular family member