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Cooperative activation of cultured vagal afferent neurons by leptin and cholecystokinin

MMPs are a family of zinc-dependent endopeptidases that degrade ECM components, while their activity is tightly controlled by their endogenous inhibitors, the TIMPs

Holst (2007)

In addition, semaglutide, liraglutide, and tirzepatide are GLP-1R agonists that are FDA-approved [69]

In 1902 they discovered in anaesthetised dogs that a chemical messenger secreted by the intestinal lining into the bloodstream helped to stimulate the pancreas to produce digestive juices whenever food or acid was introduced into the duodenum