c-Src(Phospho Tyr419) Polyclonal Antibody, 50ul[BT-AP06924] CellSafe™ Specifically phosphorylates 'Tyr-505' on LCK

Specifically phosphorylates 'Tyr-505' on LCK

Two different N-terminal and five different C-terminal protein sequences are encoded by the splice variants

The protein encoded by this gene is related to nucleoporins| a class of proteins that mediate nucleocytoplasmic transport

suggesting that it may be a good candidate for the del(5q) tumor suppressor gene

This kinase specifically activates MAPK8/JNK1 and MAPK9/JNK2| and this kinase itself is phosphorylated and activated by MAP kinase kinase kinases including MAP3K1/MEKK1| MAP3K2/MEKK2|MAP3K3/MEKK5| and MAP4K2/GCK

c-Src(Phospho Tyr419) Polyclonal Antibody, 50ul[BT-AP06924] CellSafe™ Specifically phosphorylates 'Tyr-505' on LCKThis gene is highly similar to the v src gene of Rous sarcoma virus. This proto oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine protein kinase whose activity can be inhibited by phosphorylation by c SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for