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The molecule was developed by the Australian pharmaceutical company Metabolic Pharmaceuticals (in collaboration with Monash University) and advanced through Phase I safety trials and a Phase IIb obesity efficacy trial enrolling approximately 900 participants in total

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Category 2 is the FDA's designation for bulk drug substances nominated for compounding consideration that have been identified as presenting potential safety risks and are currently ineligible for routine compounding under Section 503A

Both effects respond to morning dosing and dose reduction to 250 mcg

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