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This paradoxical improvement occurs because pain reduction outweighs any stimulatory effect on neurotransmitters

4-HNE was shown to induce GCLC with concentrations found in human plasma, suggesting that the basal GCLC expression is under regulation by products of lipid peroxidation [84]

Clin Exp Immunol 31:30, 1978

The symptoms related to the cornea are Kayser-Fleischer rings, or dark rings that appear around the iris that are caused by copper buildup in the cornea