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Why Peptides Get Attention in Repair Models Short peptide chains are frequently used in lab research because they can act as signaling modulators

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Existing evidence is limited to preliminary observations from small cohorts and short follow-up, which does not allow for firm clinical conclusions (216)

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In a neonatal rat hypoxicischemic brain injury (HIBI) model, hydrogen significantly reduced the Bax/Bcl-2 ratio by up-regulating the expression of the anti-apoptotic protein Bcl-2, while down-regulating the expression of the pro-apoptotic protein Bax and the apoptosis-executing enzyme caspase-3, leading to a reduction in apoptosis (Wang et al., 2020)