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Compared with chemically synthesized drugs, natural product-derived therapeutics offer significant advantages, including superior biocompatibility and functional diversity, attributes shaped by evolutionary optimization through long-term natural selection (Yao et al., 2017)

reported that, compared to the effects of either compound alone, the combined treatment with AS-IV and tanshinone IIA more effectively reduced lipid areas in the right common carotid artery, increased collagen content, thickened the fibrous cap, and enhanced plaque stability

Vitamin B12 is an essential nutrient that plays a vital role in red blood cell formation, brain function, and energy production

26 Again, further investigations are needed to determine optimal targeted therapies for advanced CCS

In-house softwares were developed to deconvolute the spectra associated with 15 different LMWMs (amino acids and carbohydrates, among others) [38] and 14 lipids, including cholesterol, glycerides, phospholipids and fatty acids [39]