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Most patients begin noticing improvements within the first two to four weeks of consistent use

doi: 10.1017/S0007114511004429

Pomegranate: Punicalagins reduce inflammation and fibrosis

It is important to remember that body weight is only one factor

The enterocyte FXR is the sensor of luminal bile acids and increases the secretion of the enterohormone fibroblast growth factor 19 (FGF19), which regulates liver bile acid synthesis, systemic glucose metabolism, and gallbladder motility (refilling) by activation of its receptor -klothoFGFR4 [28, 31]