EGFR(Phospho Tyr1110) Polyclonal Antibody, 20ul ROS/Nitric Oxide Detection 2006 [PubMed 16464857])

2006 [PubMed 16464857])

Ras is converted from the active GTP-bound state to the inactive GDP-bound state and no longer activates downstream pathways that regulate gene expression

Its expression has also been detected in developing CNS and testis and so the encoded protein may also play a role in neural development and spermatogenesis

Expertly designed for laboratory use

some non-protein coding and some protein coding

EGFR(Phospho Tyr1110) Polyclonal Antibody, 20ul ROS/Nitric Oxide Detection 2006 [PubMed 16464857])The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer.