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Yang Y, Zhong Z, Wang B, Wang Y (2022) Xiaoyao San ameliorates high-fat diet-induced anxiety and depression via regulating gut microbiota in mice

therefore, our conclusions focus primarily on temperature-dependent regulation of T-cell motility and associated metabolic and transcriptional changes

Unlike GLP-1 agonists that work through appetite suppression, AOD-9604 directly enhances fat cell metabolism regardless of appetite or food intake

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The apparent physiological opposition between GLP-1 and GCG does not preclude pharmacological synergy, since GLP-1/GCG dual agonists are engineered to achieve balanced receptor activation rather than simple co-administration of two counter-regulatory hormones (61,64)