AG-490 Catalog No.:M7639-2 Nafamostat mesilate inhibits extrinsic pathway

Nafamostat mesilate inhibits extrinsic pathway activity (TF-F

Molecular Weight: 328

Chemical Name: 2-Chloro-4-[(1R

3 h ours) acts in a DNA damage independent manner to activate nucleolar stress and RPA194 degradation

1038/s42003-018-0105-8

AG-490 Catalog No.:M7639-2 Nafamostat mesilate inhibits extrinsic pathwayTyrphostin AG490 is a JAK 2 specific inhibitor, which inhibits phosphorylation of EGFR and signal transducer and activator of transcription 3 [STAT 3], and subsequently reduce invasion and adhesion potential of malignant cells. The hematopoietic cancer c Kit+, Jak 2+ and non hematopoietic tumors c Kit+, HER 2+, JAK 2+ can be inhibited by the chemosensitizing agent AG490 causing programmed cell death. Product information CAS Number: 133550 30 8