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Some patients may benefit from tapering, a lower maintenance dose, or another medical strategy depending on their health history

10.1097/prs.0000000000000822 36 DebrahA

FIGURE 11 The predicted impact of the two D-amino acid impurities on the HLA-binding properties of the semaglutide peptide is supported by in vitro HLA binding studies performed and shown below (Figure 12)