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The expression of TLR2 above 80% was defined as high expression, while below 80% was defined as low expression

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GLP-1 medications work by mimicking natural incretin hormones to improve blood glucose control and reduce appetite Common side effects are gastrointestinal (nausea, vomiting, diarrhoea) rather than fluid retention Unlike thiazolidinediones, GLP-1 agonists are not associated with oedema as a recognised adverse effect Any unexplained swelling whilst taking GLP-1 medications requires medical assessment to exclude other causes Dehydration from gastrointestinal side effects is more common than fluid retention with GLP-1 therapy Table of Contents What Are GLP-1 Medications and How Do They Work

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Plasma also contains small amounts of estrogen and DHT, which like testosterone are predominantly bound to plasma proteins, and originates from the escape or leakage of these metabolites from peripheral tissues containing aromatase or 5-reductase (Swerdloff et al, 2017)

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Different G- and H-site locations in the amino-acid residue of different GSTs exert different functions

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