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Structure mechanism insights and the role of nitric oxide donation guide the development of oxadiazole-2-oxides as therapeutic agents against schistosomiasis

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Clinical trials have shown that GLP-1R agonists increase microvascular blood volume and flow in cardiac muscle, and these effects are preserved in obese individuals with vascular insulin resistance

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Cytosolic cysteine is the limiting amino acid for GSH synthesis because it has a low concentration compared to glycine and glutamate