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Most data are extrapolated from NNMT biology and animal work

Furthermore, our preliminary experiment revealed that long-term (12 weeks) supplementation of glutathione (50 mg/kg body weight) in mice did not significantly increase liver glutathione levels compared to than in controls, indicating that oral administration of glutathione does not significantly affect the glutathione levels in the liver, when sufficient amounts of glutathione can be synthesized

Thats an aspiration risk under general anesthesia

Certain gut bacteria can convert L-carnitine into compounds that later form TMAO in the liver

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