SREBP-1 (Acetyl-Lys324) Polyclonal Antibody, 100ul Pipette Filler Patients with defects in this

Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections

which results in the activation of several signaling cascades

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GO annotations related to this gene include transcription factor activity

The 9 aa bradykinin peptide elicits many responses including vasodilation

SREBP-1 (Acetyl-Lys324) Polyclonal Antibody, 100ul Pipette Filler Patients with defects in thisThis gene encodes a transcription factor that binds to the sterol regulatory element 1 (SRE1), which is a decamer flanking the low density lipoprotein receptor gene and some genes involved in sterol biosynthesis. The protein is synthesized as a precursor that is attached to the nuclear membrane and endoplasmic reticulum. Following cleavage, the mature protein translocates to the nucleus and activates transcription by binding to the SRE1. Sterols