TTK(Phospho Thr676) Polyclonal Antibody, 20ul Cell Culture Flasks This protein induces apoptosis in

This protein induces apoptosis in breast cancer cells through a caspase 2-mediated signaling pathway

but not isoform 3

A pseudogene of this gene is located on the short arm of chromosome 2

Transcripts for this gene undergo alternative splicing that results in many tissue-specific isoforms

Involved in somatic hypermutation of immunoglobulin genes

TTK(Phospho Thr676) Polyclonal Antibody, 20ul Cell Culture Flasks This protein induces apoptosis inThis gene encodes a dual specificity protein kinase with the ability to phosphorylate tyrosine, serine and threonine. Associated with cell proliferation, this protein is essential for chromosome alignment at the centromere during mitosis and is required for centrosome duplication. It has been found to be a critical mitotic checkpoint protein for accurate segregation of chromosomes during mitosis. Tumorigenesis may occur when this protein fails to