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Is haemosiderin formation a biological protective mechanism

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Pro198Leu polymorphism in the glutathione peroxidase 1 gene contributes to diabetic peripheral neuropathy in type 2 diabetes patients

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As a xanthine derivative, istradefylline acts within the basal ganglia by selectively targeting adenosine A2A receptors, which influence output pathways involving glutamate and GABA, both of which are largely regulated independently of dopamine