FAK Monoclonal Antibody, 100ul[BT-MCA0526] 3D Culture Spectrins are composed of alpha

Spectrins are composed of alpha and beta dimers that associate to form tetramers linked in a head-to-head arrangement

Two related pseudogenes have been identified on chromosome 14

Tissue-specific utilization of alternative polyA-signal has been described in literature

The encoded protein may play a role in central nervous system development by antagonizing sonic hedgehog signaling

is a major component of the basement membrane

FAK Monoclonal Antibody, 100ul[BT-MCA0526] 3D Culture Spectrins are composed of alphaThis gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal