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Some people start with injection for an active treatment phase, then maintain with oral or topical during off-cycles

That pairing runs against the usual reasoning, since slowing transit would ordinarily be expected to aggravate constipation rather than relieve it

While IGF-1 has important physiological functions, elevated levels carry potential concerns including increased cell proliferation that may support tumor growth in individuals with cancer or pre-cancerous conditions, accelerated aging processes through growth pathway activation, potential cardiovascular effects with chronic elevation, and metabolic consequences including effects on glucose and lipid metabolism

323 , F455F467 (2022)