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QPCT Rabbit Polyclonal Antibody, 20ul Immunoassays |PTM:Sumoylation on Lys-428 is promoted

SKU: 27066846119

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DKK97.20 DKK123.20

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QPCT Rabbit Polyclonal Antibody, 20ul Immunoassays |PTM:Sumoylation on Lys-428 is promotedThis gene encodes human pituitary glutaminyl cyclase which is responsible for the presence of pyroglutamyl residues in many neuroendocrine peptides. The amino acid sequence of this enzyme is 86% identical to that of bovine glutaminyl cyclase.

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Description

|PTM:Sumoylation on Lys-428 is promoted by the E3 SUMO-protein ligase CBX4

This receptor subunit forms an active heterodimeric complex with GABA-B receptor subunit 1

catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate

The chromosomal rearrangements are the most common genetic alterations in this gene| which result in creation of multiple fusion genes in tumourigenesis| including ALK (chromosome 2)/EML4 (chromosome 2)| ALK/RANBP2 (chromosome 2)| ALK/ATIC (chromosome 2)| ALK/TFG (chromosome 3)| ALK/NPM1 (chromosome 5)| ALK/SQSTM1 (chromosome

q11) with T-cell receptor alpha chain (TCRA) genes

QPCT Rabbit Polyclonal Antibody, 20ul Immunoassays |PTM:Sumoylation on Lys-428 is promotedThis gene encodes human pituitary glutaminyl cyclase which is responsible for the presence of pyroglutamyl residues in many neuroendocrine peptides. The amino acid sequence of this enzyme is 86% identical to that of bovine glutaminyl cyclase.

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